Cobra Cytotoxins: Structural Organization and Antibacterial Activity Cardiotoxins (cytotoxins, CT) are β-structured proteins isolated from the venom of cobra They consist of 59–61 amino acid residues, whose antiparallel chains form three ‘fingers’ In contrast to neurotoxins with an overall similar fold, CTs are amphiphilic
Frontiers | Cytotoxicity of Snake Venoms and Cytotoxins From Two . . . Venoms of cobras (Naja spp ) contain high abundances of cytotoxins, which contribute to tissue necrosis in cobra envenomation The tissue-necrotizing activity of cobra cytotoxins, nevertheless, indicates anticancer potentials
Cobratoxin - Wikipedia The cobras that produce the toxin live in tropical and subtropical regions of Africa and Asia The venom, produced by these snakes, is a mixture of proteins, carbohydrates, and other substances The venom is only used when the snake needs it for survival, because it costs a lot of effort to produce
The myth of cobra venom cytotoxin: More than just direct . . . - PubMed Cobra venom cytotoxin (CTX) is a non-enzymatic three-finger toxin that constitutes 40-60% of cobra venom Thus, it plays an important role in the pathophysiology of cobra envenomation, especially in local dermonecrosis The three-finger hydrophobic loops of CTX determine the cytotoxicity
The myth of cobra venom cytotoxin: More than just direct cytolytic actions Cobra venom cytotoxin (CTX) is a non-enzymatic three-finger toxin that constitutes 40–60% of cobra venom Thus, it plays an important role in the pathophysiology of cobra envenomation, especially in local dermonecrosis The three-finger hydrophobic loops of CTX determine the cytotoxicity